Mei Han

Amgen Inc.

Mei has worked in biotech industry for 20 years after she obtain her MS from Dept of Chemistry and Biochemistry, Montana State University. She is currently a Senior Scientist in the Pharmacokinetics & Drug Metabolism (PKDM) department at Amgen South San Francisco. Over the years, she has worked in different functional areas across Amgen including Analytical Sciences, Protein Sciences and PKDM. 

Her experience ranging from chromatographic (such as SEC, CEX, HIC and RP-HPLC), electrophoresis (cIEF, CE-SDS, CE-MS) and mass spectrometry analytical method development, inter- and intra- departmental method transfer such as from Analytical Sciences to QC labs, involved in IND and BLA filing; she is also experienced in small and middle scale protein purification. She implemented Capillary Electrophoresis (CE) techniques into Protein Science and PKDM departments, developed an automated immunoaffinity capture (IA)-CE-MS intact mass analysis biotransformation workflow in PKDM department to support multiple pipeline projects ranging from antibodies, fusion proteins and antibody conjugates in vitro and in vivo as well as other characterization techniques. Currently she leads the large molecule ADME team within PKDM, interacting with Project Team Representatives to support projects and serve as resource for protein characterization, analytical method development, troubleshooting and experiment planning.

Over the past 20 years she has been involved in Beckman/Sciex’s CE-SDS Analysis Kit development, providing much inputs for CE-related instrument development for multiple vendors such as PA800 Plus, iCE280, CE Infinite etc. Currently, she serves as a CE Pharm Committee member and Associate Director for CASSS.