Noemí Dorival-Garcia

Noemí holds a Ph.D. in Analytical Chemistry from the University of Granada, Spain, which was focused on the development of analytical methods for the determination of pharmaceuticals, endocrine disruptors and emerging contaminants in environmental and biological matrices. She joined the Characterisation and Comparability Lab at NIBRT in 2015 on a project entitled “Facility of the future: the plastic factory, enabling single use technologies”, focusing on the characterisation of E&L compounds from single-use technology solutions, using different mass spectrometry-based analytical techniques, and modern sample preparation approaches. In the same line of investigation, she is currently working on 2 Projects: one about “Determining the Reduction Capacity of Ultrafiltration/Diafiltration for Removing Leachables from Process Streams”, leading the the technical part, funded by Enterprise Ireland in collaboration with Janssen Sciences Ireland; and also she was awarded with a Research Grant to lead another Project about “Assessing Effects of Leachables and the Quality of Single-Use Systems in Cell and Gene Therapy Manufacturing”.

She is also involved in another research area, related to process analytical technologies for monitoring of critical quality attributes (CQAs) of recombinant proteins, being part of another project entitled “Continuous Quality – Multi-Attribute Continuous Product Characterisation for Increased Process Control”, in collaborative partnership with Pfizer, to develop an on-line real time multi-attribute CQA assessment platform using high resolution LC-MS for monoclonal antibodies and Fc fusion proteins for increased process understanding, optimisation, intensification and control.