Lake Paul

BioAnalysis, LLC

Lake, a NIH Ruth L. Kirschstein Fellow, obtained his PhD in Structural Biology and Biophysics from Purdue University under Cynthia Stauffacher. After his PhD, he joined a Mass Spectrometric-focused lab at NIEHS for his post doctoral studies. After his post-doctoral studies, he created the Biophysical Analysis Lab at the Bindley Bioscience Center where he introduced a comprehensive and successful biophysics analytical program that included AUC, CD, ITC, DLS, DSC, SPR, BLI and MALLS techniques. He was also the Director of the Purdue Proteomic Facility, where he implemented new analytical methods for looking at large proteomic data, PTMs, de novo sequencing and quantitation (MRM/SRM, LFQ and isotopic labeling). Lake went into industrial sector where he led programs that focused on discovery, process development, cGMP method development and validation, cGMP manufacturing and Quality Control for a variety of systems: Small Molecules, Proteins, mAbs, ADCs to Gene Therapy. Lake started his own CRO company: BioAnalysis, LLC, focusing on high-level biophysical and analytical chemistry collaborations. His deep expertise: >25 peer reviewed publications, business acumen, CMC strategy, BLA submissions, QA/C, Interacting with the FDA and EMEA, and analytical method development/validation has proven to be an invaluable resource to his clients.