Bioassays for Bispecifics – Double the Trouble or Double the Fun?

The structures and functions of modern biotherapeutics are becoming increasingly complex. A new generation of diverse multi-modal molecules has quickly emerged, where single molecules can bind multiple targets, harbor multiple activities, have combinatorial/synergistic activities, or all of the above. The complexity of multi-modal biotherapeutics brings about new challenges for bioassay development, as well as exciting opportunities for the application of novel assay formats and technologies.