Noemi Dorival-Garcia

The National Institute for Bioprocessing Research and Training (NIBRT)

Noemí holds a PhD in Analytical Chemistry from the University of Granada, Spain, which was focused on the development of analytical methods for the determination of pharmaceuticals, endocrine disruptors and emerging contaminants in environmental and biological matrices. She joined the Characterisation and Comparability Lab at NIBRT in 2015 on a project entitled “Facility of the future: the plastic factory, enabling single use technologies”, focusing on the characterisation of E&L compounds from single-use technology solutions, using different mass spectrometry-based analytical techniques, and modern sample preparation approaches. Currently, she leads E&L projects, related to the generation and monitoring of E&L during upstream stages, but also investigation of removal mechanisms during downstream steps, as well as she has already begun investigation to assess effects of leachables and the evaluation of the quality of single-use systems in cell and gene therapy manufacturing. Noemí is also involved in the research area related to process analytical technologies for the monitoring of critical quality attributes of recombinant proteins, being dedicated to projects related to the development of on-line automated process control monitoring systems for multiple critical quality attributes continuous product characterisation, using high resolution LC-MS techniques for increased process understanding, optimisation, intensification and control.