CE and LCMS are now being used to characterize gene therapy products and oligonucleotides under development. From this presentation you will:
• Understand how both CE and LCMS are being used to profile viral capsid proteins to gain better understanding of gene therapy product potency. • Discover how CE is now being used to profile full and empty viral vectors used in gene therapy and profile the genome integrity of viral particles. • Find out how CE and LCMS is being used to detect and characterize oligonucleotides including CE profiling of plasmids (used in gene therapy) and RNA products (CRISPR) and the detection and characterization of smaller oligonucleotides by LCMS.