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A bioassay case study summarizing the challenges in setting the control system of a combination product of two highly similar monoclonal therapeutic antibodies targeting the same cellular antigen: from similar modes of action and synergistic effect to the control of each molecule bioactivity in vit…
Viral pathogens can cause wide-spread pandemics (influenza type A, SARS-CoV-2), may have high mortality rates (Ebola virus) and pose enormous health and socioeconomic risks. Certain viruses can also be used as agents for bioterrorism…