Quantitative Proteomics for Understanding Histone Mutations in Human Disease (45 minutes)
Q&A (15 minutes)
Session Speaker: Benjamin Garcia, Washington University in St. Louis
Importance of Disulfide Bond re-arrangement in vitro and in vivo: Evidence and Approaches to Address It
Franta Hubálek, Novo Nordisk A/S
Development of a Rapid and Automated, Compliance Ready Workflow for Full Sequence Coverage of RNAi Therapeutics
Jennifer Nguyen, Alnylam Pharmaceuticals
Elucidation, Characterization and Monitoring of a Unique Tyrosine Sulfation Post-Translational Modification During Bispecific Antibody Process Development and Scaleup
David Mahon, Bristol-Myers Squibb Company
Technical Seminar Lunch & Learn Sessions are for Mass Spec attendees only. HOS attendees and those not wishing to attend should grab their lunch and proceed to the Explore Room (Floor 2).
High-Order Structure Characterization of Membrane Proteins Using Benzoyl Fluoride Footprinting
Mengqi Chai, Washington University in St. Louis
In Depth Characterization of Biologics Through a Combination of Mass Spectrometry and Molecular Modeling
Naresh Chennamsetty, Bristol-Myers Squibb Company
Protein Footprinting for Structural Biology in Complex Model Systems
Lisa Jones, University of California San Diego
Complementary Backbone and Side Chain Analysis of Drug – Protein Interactions Combining Hydrogen/Deuterium Exchange and Protein Oxidative Mass Spectrometry
Yan Sun, Albert Einstein College of Medicine
Mass Spectrometry Enables More Definitive Process & Product Development Towards Well-Characterized Biotherapeutics: A Personal Account
Jason Rouse, Pfizer, Inc.
Applications of Mass Spectrometry in CRISPR based Cell Therapy and Gene Editing Therapy
Bo Yan, Beam Therapeutics
LC-MS/MS as a Potency Assay for mRNA Vaccines
Aline Dörrbaum, BioNTech SE
Proteomic Approaches for Characterization of Live Biotherapeutic Escherichia coli Nissle Products from Fermentation to Therapeutic Activity
Steven Bruckbauer, Synlogic Operating Company
Mass Spec attendees should grab their lunch and beverages and return to the general session room if they plan on attending the vendor showcase.
*The vendor showcases are not part of the HOS Symposium.
HOS attendees should grab their lunch and proceed to the meal room to eat.
Wayne Hicks, CBER, FDA
Frances Namuswe, CDER, FDA
Sarah Rogstad, CDER, FDA