Klaus Kronsbein

Klaus Kronsbein is a PhD student at Boehringer Ingelheim specializing in analytics of biopharmaceuticals. His work centers on using Design of Experiments (DoE) in the context of forced degradation studies (FDS) to build clearer and more reliable structure-function relationship (SFR) models. This statistical approach introduces greater variance into forced degradation studies, allowing for a more accurate assessment of how specific molecular modifications affect a drug's function. His recent publication, "Advancing Forced Degradation Studies: Design of Experiments for Enhanced Structure-Function Relationship Analysis in Biotherapeutics," details this enhanced methodology for more insightful data interpretation during biotherapeutic development.